Derek Lowe -- Of the fantastic "In The Pipeline" blog with Science disagrees with the FDA approval; http://blogs.sciencemag.org/pipeline/archives/2016/09/20/s

Derek Lowe -- Of the fantastic "In The Pipeline" blog with Science disagrees with the FDA approval; http://blogs.sciencemag.org/pipeline/archives/2016/09/20/sarepta-gets-an-approval-unfortunately http://blogs.sciencemag.org/pipeline/archives/2016/09/20/sar... He's an excellent read if anyone wants to keep up with things in the Pharma and regulatory world. He's probably more famous for his "Things I Won't Work With" series that I've seen linked to a few times on HN. > And he’s just getting warmed up, if that’s the right phrase to use for something that detonates things at -180C (that’s -300 Fahrenheit, if you only have a kitchen thermometer). The great majority of Streng’s reactions have surely never been run again. The paper goes on to react FOOF with everything else you wouldn’t react it with: ammonia (“vigorous”, this at 100K), water ice (explosion, natch), chlorine (“violent explosion”, so he added it more slowly the second time), red phosphorus (not good), bromine fluoride, chlorine trifluoride (say what?), perchloryl fluoride (!), tetrafluorohydrazine (how on Earth. . .), and on, and on. If the paper weren’t laid out in complete grammatical sentences and published in JACS, you’d swear it was the work of a violent lunatic. http://blogs.sciencemag.org/pipeline/archives/2010/02/23/things_i_wont_work_with_dioxygen_difluoride http://blogs.sciencemag.org/pipeline/archives/2010/02/23/thi...