3 ms·
That is the current standard (Ph 3 clinical trials against standard of care). There are rare exceptions to this, but the ones I can think of are drugs for which
by jonlucc 10y ago
That is the current standard (Ph 3 clinical trials against standard of care). There are rare exceptions to this, but the ones I can think of are drugs for which there is no current standard and drugs for which the current standard doesn't match the intended indication. In modern medicine, we don't just take diagnosed patients who meet criteria for a trial and let them progress without disease.
- ekianjo 10y agoThats why I mentioned "have been". But such drugs are still being sold.patented and used.
- jonlucc 10y agoYes; our system makes it very difficult to put horses back in the barn. I heard one physician say that Tylenol would not make it through today, or at the very least it would be prescription, because of the slim toxicity margin.
- Retric 10y agoTylenol causes ~56,000 emergency room visits, 2,600 hospitalizations, and ~450 deaths per year. IMO, at a minimum it should have much stronger warning labels on it.