Excel can(at this day) handle 1,048,576 rows which is 2^20. If you really need to work on bigger DBs than that I'd recommend using Power Pivot(natively included

Excel can(at this day) handle 1,048,576 rows which is 2^20. If you really need to work on bigger DBs than that I'd recommend using Power Pivot(natively included in Excel 2016) which is supposed to handle way more than 2^20 rows.