The isolation never bothered me. I have a few close friends, and a wonderful wife, and i tend to be "introverted" in the sense that it's really draining for me

The isolation never bothered me. I have a few close friends, and a wonderful wife, and i tend to be "introverted" in the sense that it's really draining for me to be in a social setting for too long, so working from home has been perfect for all these years. That being said, the "you work from home so you should be able to handle X" really gets to me. I actually have less flexibility than it sounds like you do, it was never explicitly said, but most of us work 9-ish to 5-ish monday-ish through friday-ish. It was something that my wife and I needed to work out on our own, because she would expect me to be able to run out and pick up prescriptions during the week, or would ask me frequently to go to the store to grab something for dinner. And I'd feel like an ass for saying no, because on some level she is right, I do have the ability, and it is easier for me, but it still impacts my day a lot to interrupt my work to run to the store. We have found a good medium now, but it was a common argument for a while.