4 ms·

>despite MDMA never having been reasonably blamed for any death You're just plain wrong here. Ecstasy is a dangerous drug that can cause overheating, dehydrati

>despite MDMA never having been reasonably blamed for any death You're just plain wrong here. Ecstasy is a dangerous drug that can cause overheating, dehydration, and other very serious conditions that can and do result in death. Further, the drug's effects discourage the behaviors, like eating and drinking water in reasonable quantities, that are essential to preventing those conditions. With their sense of hunger and thirst totally haywire, some people try to overcompensate and end up dying from too much water. And as for the long-term effects of regular MDMA use: persistent brain damage and loss of cognitive function.

jeremyjh 10y ago
>drinking too much water and dying Citation needed.
- marcoperaza 10y ago
  Definition: Hyponatremia is a condition that occurs when the level of sodium in your blood is abnormally low. Sodium is an electrolyte, and it helps regulate the amount of water that's in and around your cells. http://www.mayoclinic.org/diseases-conditions/hyponatremia/basics/definition/con-20031445 http://www.mayoclinic.org/diseases-conditions/hyponatremia/b... Risk factors: Certain drugs. Medications that increase your risk of hyponatremia include thiazide diuretics as well as some antidepressants and pain medications. In addition, the recreational drug Ecstasy has been linked to fatal cases of hyponatremia. http://www.mayoclinic.org/diseases-conditions/hyponatremia/basics/risk-factors/con-20031445 http://www.mayoclinic.org/diseases-conditions/hyponatremia/b... While staying hydrated can reduce the risk of heat stroke associated with MDMA, the drug can also cause the body to retain water, so drinking too much can lead to a potentially fatal electrolyte imbalance. http://healthland.time.com/2013/09/03/concert-deaths-five-myths-about-the-drug-molly/ http://healthland.time.com/2013/09/03/concert-deaths-five-my... More common, ecstasy has led to serious hyponatremia and hyponatremia-associated deaths. Hyponatremia in these cases is due to a "perfect storm" of ecstasy-induced effects on water balance. Ecstasy leads to secretion of arginine vasopressin as well as polydipsia as a result of its effects on the serotonergic nervous pathways. Compounding these effects are the ready availability of fluids and the recommendation to drink copiously at rave parties where ecstasy is used. The effects of ecstasy on the kidney as well as therapeutic measures for the treatment of ecstasy-induced hyponatremia are presented. http://www.ncbi.nlm.nih.gov/pubmed/18684895 http://www.ncbi.nlm.nih.gov/pubmed/18684895
  - ddeck 10y ago
    >Risk factors: Certain drugs... Additional risk factor: Poorly thought out radio contests: "A 28-year-old woman found dead hours after taking part in a radio station's water-drinking contest died of water intoxication, the coroner's office said Saturday" [1] [1] http://articles.latimes.com/2007/jan/14/local/me-water14 http://articles.latimes.com/2007/jan/14/local/me-water14
    - marcoperaza 10y ago
      What point are you trying to get at here? Every stupid thing that a drug can make you do has also been done by someone sober at some point.
  - deleted 10y ago
    [deleted]
taneq 10y ago
Unless you go nutso and drink stupid amounts of water, you' re not in any danger. The danger is that everyone tells you "oh you could get dehydrated, drink as much water as you can" and some people follow this advice literally when pinging. Drink 500mL-1L per hour and you'll be fine. In my own experience you run hot but your thermoregulation still works so you'll naturally seek cooler spaces when you start overheating - this is why clubs/raves have "chillout zones". I can't speak to long term effects, I only took it a few times at intervals of a few months. In my experience, MDMA is the opposite of addictive - if you've had a good night on it, taking more will do nothing for you for a few weeks.
sparky1990 10y ago
Ecstasy is really not a very dangerous drug. https://www.theguardian.com/commentisfree/2015/dec/08/is-ecstasy-really-that-dangerous-all-your-questions-answered https://www.theguardian.com/commentisfree/2015/dec/08/is-ecs... http://www.telegraph.co.uk/news/uknews/law-and-order/4537874/Ecstasy-no-more-dangerous-than-horse-riding.html http://www.telegraph.co.uk/news/uknews/law-and-order/4537874... David Nutt has spoken widely and very entertainingly about drugs and their relative harms. This is an excellent lecture he has done a number of places on politics and drug policy: https://www.youtube.com/watch?v=gkcO_wJ9yKo&spfreload=10 https://www.youtube.com/watch?v=gkcO_wJ9yKo&spfreload=10 Nutt also founded the Independent Scientific Committee on Drugs: http://www.drugscience.org.uk http://www.drugscience.org.uk This is a very good source for accurate information about drug risks and harm reduction.
deleted 10y ago
[deleted]

jeremyjh 10y ago

>drinking too much water and dying Citation needed.

marcoperaza 10y ago
Definition: Hyponatremia is a condition that occurs when the level of sodium in your blood is abnormally low. Sodium is an electrolyte, and it helps regulate the amount of water that's in and around your cells. http://www.mayoclinic.org/diseases-conditions/hyponatremia/basics/definition/con-20031445 http://www.mayoclinic.org/diseases-conditions/hyponatremia/b... Risk factors: Certain drugs. Medications that increase your risk of hyponatremia include thiazide diuretics as well as some antidepressants and pain medications. In addition, the recreational drug Ecstasy has been linked to fatal cases of hyponatremia. http://www.mayoclinic.org/diseases-conditions/hyponatremia/basics/risk-factors/con-20031445 http://www.mayoclinic.org/diseases-conditions/hyponatremia/b... While staying hydrated can reduce the risk of heat stroke associated with MDMA, the drug can also cause the body to retain water, so drinking too much can lead to a potentially fatal electrolyte imbalance. http://healthland.time.com/2013/09/03/concert-deaths-five-myths-about-the-drug-molly/ http://healthland.time.com/2013/09/03/concert-deaths-five-my... More common, ecstasy has led to serious hyponatremia and hyponatremia-associated deaths. Hyponatremia in these cases is due to a "perfect storm" of ecstasy-induced effects on water balance. Ecstasy leads to secretion of arginine vasopressin as well as polydipsia as a result of its effects on the serotonergic nervous pathways. Compounding these effects are the ready availability of fluids and the recommendation to drink copiously at rave parties where ecstasy is used. The effects of ecstasy on the kidney as well as therapeutic measures for the treatment of ecstasy-induced hyponatremia are presented. http://www.ncbi.nlm.nih.gov/pubmed/18684895 http://www.ncbi.nlm.nih.gov/pubmed/18684895
- ddeck 10y ago
  >Risk factors: Certain drugs... Additional risk factor: Poorly thought out radio contests: "A 28-year-old woman found dead hours after taking part in a radio station's water-drinking contest died of water intoxication, the coroner's office said Saturday" [1] [1] http://articles.latimes.com/2007/jan/14/local/me-water14 http://articles.latimes.com/2007/jan/14/local/me-water14
  - marcoperaza 10y ago
    What point are you trying to get at here? Every stupid thing that a drug can make you do has also been done by someone sober at some point.
- deleted 10y ago
  [deleted]

taneq 10y ago

Unless you go nutso and drink stupid amounts of water, you' re not in any danger. The danger is that everyone tells you "oh you could get dehydrated, drink as much water as you can" and some people follow this advice literally when pinging. Drink 500mL-1L per hour and you'll be fine. In my own experience you run hot but your thermoregulation still works so you'll naturally seek cooler spaces when you start overheating - this is why clubs/raves have "chillout zones". I can't speak to long term effects, I only took it a few times at intervals of a few months. In my experience, MDMA is the opposite of addictive - if you've had a good night on it, taking more will do nothing for you for a few weeks.

sparky1990 10y ago

Ecstasy is really not a very dangerous drug. https://www.theguardian.com/commentisfree/2015/dec/08/is-ecstasy-really-that-dangerous-all-your-questions-answered https://www.theguardian.com/commentisfree/2015/dec/08/is-ecs... http://www.telegraph.co.uk/news/uknews/law-and-order/4537874/Ecstasy-no-more-dangerous-than-horse-riding.html http://www.telegraph.co.uk/news/uknews/law-and-order/4537874... David Nutt has spoken widely and very entertainingly about drugs and their relative harms. This is an excellent lecture he has done a number of places on politics and drug policy: https://www.youtube.com/watch?v=gkcO_wJ9yKo&spfreload=10 https://www.youtube.com/watch?v=gkcO_wJ9yKo&spfreload=10 Nutt also founded the Independent Scientific Committee on Drugs: http://www.drugscience.org.uk http://www.drugscience.org.uk This is a very good source for accurate information about drug risks and harm reduction.

deleted 10y ago

[deleted]