There were no self-destruct systems on the shuttle orbiter, though there were on the solid rocket boosters and external fuel tank. They were used only once, on

There were no self-destruct systems on the shuttle orbiter, though there were on the solid rocket boosters and external fuel tank. They were used only once, on the Space Shuttle Challenger after the orbiter broke up, but the SRB's were still burning in an uncontrolled manner.