5 ms·

For anyone that may be interested, you can currently get a very good amyloid plaque reducing drug over-the-counter. [1] It is generally recognized as safe beyon

by tcoppi 10y ago

For anyone that may be interested, you can currently get a very good amyloid plaque reducing drug over-the-counter. [1] It is generally recognized as safe beyond a mild stimulatory effect, but don't take it while trying to get pregnant or pregnant. It seems like these types of drugs are best used for prevention rather than a cure, so I've been taking it for a year or so now even though I'm not even 30, and plan to continue for the rest of my life. I've lost quite a few relatives to Alzheimer's/dementia, so it is pretty cheap "insurance" to me, even if it turns out it just makes expensive pee. 1. https://examine.com/supplements/centrophenoxine/ https://examine.com/supplements/centrophenoxine/

Retric 10y ago
Generally recognized as safe does not mean it's a good idea to take something for 40+ years. If you did a 3 year in depth study on new, mild smokers (under 4 per day), it would probably look safe.
- tcoppi 10y ago
  You're right, it could turn out to be a horrible idea. Based on the compounds involved and how they work in the body, I don't think so, but please do your own research as to its safety and efficacy, don't take my word for it.
melling 10y ago
At what age? If it's not too young, you still have 30-40 years of additional research on your side. There is a genetic predisposition in some families. https://www.statnews.com/2016/04/12/alzheimers-disease-colombia/ https://www.statnews.com/2016/04/12/alzheimers-disease-colom... Perhaps you should participate in a study, if possible? There's an interesting documentary on HBO: http://www.hbo.com/alzheimers/about-the-project.html http://www.hbo.com/alzheimers/about-the-project.html I believe BioGen's drug is discussed in the movie.
- tcoppi 10y ago
  I'd have to look, but most of them started developing symptoms in their 60s and it had progressed to needing full-time care by their 70s, so not super-early onset but early enough to be pretty devastating. I hadn't thought about participating in a study, but that sounds interesting. I'll have to look into it.
adambmedia 10y ago
Disclaimer: this is not medical advice and I am not a medical professional. If the long-term protective benefit of the otc drug specifically as it relates to AD has not been studied, don't start taking it under 30. What has been studied are the links between your lifestyle and both protection from disease onset, and maintenance of cognitive function at the highest possible level throughout the early stages of disease. Stay smart. Always learn. Be physically active. Challenge yourself. Also, as treatments emerge over the next 30 years, the barrier to adoption will be the social stigma and an education problem. People don't want to get diagnosed for Alzheimer's Disease. Geriatric Psychs lament that family members are bringing in their loved ones nearly 100% of the time. Preventative drugs, as they become available, need to be taken early, yet, the earliest phases of the disease are difficult to disambiguate from normal cognitive decline that occurs with aging. Add in the fear - you just don't want to know - and you get most patients arriving to diagnosis too late. You're already on the right track by being confident, proactive, and taking responsibility to do what you can to remain as healthy as possible throughout your life. Don't stop.
deleted 10y ago
[deleted]

by tcoppi 10y ago

Retric 10y ago

Generally recognized as safe does not mean it's a good idea to take something for 40+ years. If you did a 3 year in depth study on new, mild smokers (under 4 per day), it would probably look safe.

tcoppi 10y ago
You're right, it could turn out to be a horrible idea. Based on the compounds involved and how they work in the body, I don't think so, but please do your own research as to its safety and efficacy, don't take my word for it.

melling 10y ago

At what age? If it's not too young, you still have 30-40 years of additional research on your side. There is a genetic predisposition in some families. https://www.statnews.com/2016/04/12/alzheimers-disease-colombia/ https://www.statnews.com/2016/04/12/alzheimers-disease-colom... Perhaps you should participate in a study, if possible? There's an interesting documentary on HBO: http://www.hbo.com/alzheimers/about-the-project.html http://www.hbo.com/alzheimers/about-the-project.html I believe BioGen's drug is discussed in the movie.

tcoppi 10y ago
I'd have to look, but most of them started developing symptoms in their 60s and it had progressed to needing full-time care by their 70s, so not super-early onset but early enough to be pretty devastating. I hadn't thought about participating in a study, but that sounds interesting. I'll have to look into it.

adambmedia 10y ago

Disclaimer: this is not medical advice and I am not a medical professional. If the long-term protective benefit of the otc drug specifically as it relates to AD has not been studied, don't start taking it under 30. What has been studied are the links between your lifestyle and both protection from disease onset, and maintenance of cognitive function at the highest possible level throughout the early stages of disease. Stay smart. Always learn. Be physically active. Challenge yourself. Also, as treatments emerge over the next 30 years, the barrier to adoption will be the social stigma and an education problem. People don't want to get diagnosed for Alzheimer's Disease. Geriatric Psychs lament that family members are bringing in their loved ones nearly 100% of the time. Preventative drugs, as they become available, need to be taken early, yet, the earliest phases of the disease are difficult to disambiguate from normal cognitive decline that occurs with aging. Add in the fear - you just don't want to know - and you get most patients arriving to diagnosis too late. You're already on the right track by being confident, proactive, and taking responsibility to do what you can to remain as healthy as possible throughout your life. Don't stop.

deleted 10y ago

[deleted]