If you'd like to be closer to the East Coast, the Scranton area is beginning to gain traction, as it's very accessible from Boston, New York, and Philadelphia.

If you'd like to be closer to the East Coast, the Scranton area is beginning to gain traction, as it's very accessible from Boston, New York, and Philadelphia. Cost of living is rock-bottom (an actual Victorian mansion can be <$500k, and a beautiful rental apartment in one of the uber-trendy small towns such as Pittston can be had for $800/mo), the food is excellent, and there's very easy access to beautiful areas for hiking, biking, and fishing with multiple state parks and campgrounds within a short drive. The healthcare is among the best outside of a major medical center. Public education is generally very high quality, with private high schools, universities, and the medical school essentially free to high-performing or low income students. Community banks are highly prevalent, and they're very willing to make small business loans to pre-profit companies with sufficient credibility. The area is also remarkably entrepreneurial, to the point where one is lionized for the mere act of forming a company, from a tech startup to a restaurant. There's also been some solid tech exits, such as Solid Cactus, which was for an undisclosed sum, but they were already raking in annual profit in excess of $2 million.