http://www.subituqueja.com http://www.subituqueja.com (in spanish) http://pythonregex.appspot.com http://pythonregex.appspot.com Both running Python + Django 1

http://www.subituqueja.com http://www.subituqueja.com (in spanish) http://pythonregex.appspot.com http://pythonregex.appspot.com Both running Python + Django 1.1.1 (with Google App Engine Django Helper, http://code.google.com/p/google-app-engine-django/ http://code.google.com/p/google-app-engine-django/) I don't know if they are "big", but you can see app engine in action there.