Yes but it's also a practical psychological question. A person can come to a mental state where nothing in life interests them yet they wish there was something

Yes but it's also a practical psychological question. A person can come to a mental state where nothing in life interests them yet they wish there was something they enjoyed. So, although possibly mundane, there is a point of view where the question "does anything in life have meaning" is less interesting than the question "is everything ok".