Sounds like my experience with USB keyboard and mouse not working after a restart. They work in the BIOS, but as soon as the Windows loading screen appears, the

Sounds like my experience with USB keyboard and mouse not working after a restart. They work in the BIOS, but as soon as the Windows loading screen appears, they stop working. I restored my PC to a restore point, they worked again. After another restart, they stopped working. I reset my PC, losing apps and settings. They worked again until another restart. I had set up remote access, so I was able to use my trusty MacBook to remote in and remove every "USB Root Hub" in Device Manager, then let Windows self-heal. That caused my mouse and keyboard to work again. So basically I have to keep a secondary PC around in case my Windows 10 PC ever reboots, so I can have a mouse and keyboard. I saw lots of posts online about keyboard and mouse not working on boot in Windows 10, but unplugging/replugging seemed to work for those people. It did nothing for me. I saw advice to disable fast boot, but even after doing that, on restart they stopped working. It also seems pretty suspect that the keyboard and mouse work fine in my BIOS and only stop responding after the Windows 10 spinner appears.