This depends on the person talking. In work situations I have dealt with some (rare) people who will just talk over you if you try to politely insert a suggest

This depends on the person talking. In work situations I have dealt with some (rare) people who will just talk over you if you try to politely insert a suggestion or a question. Very occasionally, the right response is to interrupt them impolitely. Much more often the best thing is to let them finish. It's an almost passive-aggressive solution, but sometimes it's the best you can do.