3 ms·
By 'nanorobot' they mean bacteria. >We show that when MC-1 cells bearing covalently bound drug-containing nanoliposomes were injected near the tumour in severe
by astazangasta 10y ago
By 'nanorobot' they mean bacteria.
>We show that when MC-1 cells bearing covalently bound drug-containing nanoliposomes were injected near the tumour in severe combined immunodeficient beige mice and magnetically guided, up to 55% of MC-1 cells penetrated into hypoxic regions of HCT116 colorectal xenografts. Approximately 70 drug-loaded nanoliposomes were attached to each MC-1 cell. Our results suggest that harnessing swarms of microorganisms exhibiting magneto-aerotactic behaviour can significantly improve the therapeutic index of various nanocarriers in tumour hypoxic regions.
So they load these little guys up with drug and use magnets to guide them into the tumor, which kind of works in SCID mice, although you'll note they make no claims about ability to actually kill or shrink tumors.
This news piece is awful, incidentally, but what else is new.
- chewymouse 10y agoUnfortunately, the original article is inaccessible both from a paywall standpoint ($32 at http://www.nature.com/nnano/journal/vaop/ncurrent/full/nnano.2016.137.html http://www.nature.com/nnano/journal/vaop/ncurrent/full/nnano...) and also from a technical standpoint.
- iak8god 10y agoIt is available on sci-hub http://sci-hub.bz/10.1038/nnano.2016.137 http://sci-hub.bz/10.1038/nnano.2016.137
- jcoffland 10y agoThe criteria for calling something a robot is apparently very broad. Poor journalism indeed. How can pop-sci be reigned in?
- astazangasta 10y agoGood question: (1) open access so people can read the original research, (2) better writing therein so people will actually understand what they read, will surely help.
- jessriedel 10y ago> By 'nanorobot' they mean bacteria. Yea, I think this is a little like calling a horse-drawn carriage an automobile.