The potential benefits of combining the properties of the two (circuits that are more robust even when damaged, etc.) are intriguing, but there aren't any menti

The potential benefits of combining the properties of the two (circuits that are more robust even when damaged, etc.) are intriguing, but there aren't any mentions of the potential negatives that will also undoubtedly arise. Will such circuits also be more prone to crosstalk? Will they be sensitive to different lighting conditions?