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FDR was practically invented to handle the multiple testing issues that accompany analyzing array data. I think what OP was implying was that there is no way th
by hyperbovine 10y ago
FDR was practically invented to handle the multiple testing issues that accompany analyzing array data. I think what OP was implying was that there is no way that you are going to get a GWAS paper into Nature Genetics in 2016 without performing the appropriate statistical corrections. Literally everyone in the field is aware of this issue. In other words, give the authors and referees a little credit.
- erdevs 10y agoI did not mean to imply that this paper was due extra skepticism in particular. Indeed, I tried to give the paper due praise for seeming to be more rigorous than many other GWASs. And, yes indeed, false discovery rate has been a huge issue which the field has highlighted... that is my point. Caution has been warranted here historically, and it continues to be warranted even today.