The important note here is that it's something you can do during your "harvest phase" (after you've established a name for yourself and have job security by ski

The important note here is that it's something you can do during your "harvest phase" (after you've established a name for yourself and have job security by skills and reputation) but not when you're starting out. For an average 22-year-old to work from home would be a bad idea. You need to be in an office so you can make connections and become the protege of someone who can teach you and look out for your career (and if you don't find such a person, jump ship every 8-12 months). If you work in an office, you can generate some affinity and loyalty (sometimes). People might feel personally betrayed if you leave, which is good, because it means they'll look out for your career. If you're working remotely, you're exchanging work for money. This is great if you're established, because you can get a lot done in a fraction of the traditional 40-hour week if you set your own hours. It's bad if you're not well-established, because your likelihood of happening across someone who will protect your career is low.