> 1 successful unicorn in a portfolio of 100 would be worth it, and you could have 15+ years to think without any pressure to publish I am totally convinced th

> 1 successful unicorn in a portfolio of 100 would be worth it, and you could have 15+ years to think without any pressure to publish I am totally convinced this is the way to go. If you look into successful people and organisations like Alfred Sanger, Cold Spring Harbor or Bell Labs they operated like this. There's no other way to implement Hamming's You and Your Research advice. Small groups, no middle management, no short-term goals, no paper optimization! I do research at a world class university. Previously I was in pretty decent ones ranking in the bottom top #100. They all have the same issues. It is very frustrating. If YC/Thiel/Musk decided to fund OpenX (for X in Bio, Renewables and a few others) the world would be a much better place in 50 years time. I have lost my faith in universities as an applied research place.