4 ms·

A Gel That's Revolutionizing Pain Treatment

88 points by kposehn 10y ago

auganov 10y ago
Abstract of the actual paper: https://www.ncbi.nlm.nih.gov/pubmed/26268315 https://www.ncbi.nlm.nih.gov/pubmed/26268315
mrfusion 10y ago
I wonder if this would be useful for gum disease? My reading seems to suggest it's more the inflammatory response to the bacteria that causes gum problems rather tha themselves.
- Aelinsaar 10y ago
  Yep, gum recession, is mostly caused by repeated inflammation, and not direct action of the bacteria, while dental carries are generally a result of the metabolic byproducts leaching the enamel. Buuuuut... the production of plaque and tartar is damaging too, so just shutting down part of the immune response (inflammation), might not be a good thing in that case.
dredmorbius 10y ago
Clickbait: It's an injected, inflammation-activated hydrogel. So the trick isn't that there's some specific compound which, when gelled, does the trick, but the gelling mechanism itself which releases medication when needed. As I read the article. Which, even past the null-content headline, delivers little clarity on the concept.
- ec109685 10y ago
  How is it not revolutionizing paint treatment?
  - dredmorbius 10y ago
    Clickbait doesn't (necessarily) apply to the quality of the content. It does, however, apply to the headline tease. "A <foo>", "This guy...", "A state...", etc., are all needlessly ambiguous phrases. They should be replaced with the subject they refer to. Apparently Atlantic Monthly are joining a trend already beaten to death by the Washington Post. And again, there are quite good stories ruined IMO by exceptionally poor heads.
    - mpbm 10y ago
      Seemed like an okay title to me. They summarized the article at a non-technical level. That's the same title I would have written to summarize it. Maybe I wouldn't have used the word "revolutionary", but I already ignore that word whenever I see it.
Emmanuelkanos 10y ago
Sounds like good progress.
lsh 10y ago
the whole paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825054/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825054/

88 points by kposehn 10y ago

Abstract of the actual paper: https://www.ncbi.nlm.nih.gov/pubmed/26268315 https://www.ncbi.nlm.nih.gov/pubmed/26268315

I wonder if this would be useful for gum disease? My reading seems to suggest it's more the inflammatory response to the bacteria that causes gum problems rather tha themselves.

Aelinsaar 10y ago
Yep, gum recession, is mostly caused by repeated inflammation, and not direct action of the bacteria, while dental carries are generally a result of the metabolic byproducts leaching the enamel. Buuuuut... the production of plaque and tartar is damaging too, so just shutting down part of the immune response (inflammation), might not be a good thing in that case.

dredmorbius 10y ago

Clickbait: It's an injected, inflammation-activated hydrogel. So the trick isn't that there's some specific compound which, when gelled, does the trick, but the gelling mechanism itself which releases medication when needed. As I read the article. Which, even past the null-content headline, delivers little clarity on the concept.

ec109685 10y ago
How is it not revolutionizing paint treatment?
- dredmorbius 10y ago
  Clickbait doesn't (necessarily) apply to the quality of the content. It does, however, apply to the headline tease. "A <foo>", "This guy...", "A state...", etc., are all needlessly ambiguous phrases. They should be replaced with the subject they refer to. Apparently Atlantic Monthly are joining a trend already beaten to death by the Washington Post. And again, there are quite good stories ruined IMO by exceptionally poor heads.
  - mpbm 10y ago
    Seemed like an okay title to me. They summarized the article at a non-technical level. That's the same title I would have written to summarize it. Maybe I wouldn't have used the word "revolutionary", but I already ignore that word whenever I see it.

Emmanuelkanos 10y ago

Sounds like good progress.

lsh 10y ago

the whole paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825054/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825054/