What trouble have you had with PyQt? I've never had any issue installing PyQt (or PySide) whatsoever, though I usually use Conda [1] with the Anaconda Python d

What trouble have you had with PyQt? I've never had any issue installing PyQt (or PySide) whatsoever, though I usually use Conda [1] with the Anaconda Python distribution, rather than the system default (which you shouldn't use, IIRC) or the official one from Python.org. The easiest way to get started is probably with the Miniconda [2] Python distribution. I'm not sure if Conda pulls down Qt, though, or if you have to install that yourself (e.g. via Homebrew). [1]: https://github.com/conda/conda https://github.com/conda/conda [2]: http://conda.pydata.org/miniconda.html http://conda.pydata.org/miniconda.html