3 ms·

I've heard that the headache is due to a lack of choline, and that most people should be taking a choline supplement with their racetams.

itistoday 17y ago
I think I read that as well, but decided against it because the literature wasn't convincing enough (i.e., hearsay on forum posts), and I wasn't thrilled with ingesting, and possibly becoming dependent on so many substances.
- metamemetics 17y ago
  Choline is a natural compound, you can get it by eating eggs. Most people take it as a supplement the same time with piracetam, you can buy them combined as well. It's definitely discussed in research as well as forums: http://www.ncbi.nlm.nih.gov/pubmed/7301036 http://www.ncbi.nlm.nih.gov/pubmed/7301036 "The results of these studies demonstrate that the effects of combining choline and piracetam are quite different than those obtained with either drug alone"
  - itistoday 17y ago
    Thanks for the pubmed link, didn't see that. As far as choline goes, I eat an egg every day, and get my vitamins and minerals from fresh fruits, veggies and legumes. Just as you can obtain Vitamin-C or choline from a supplement, so too can you obtain them from natural sources. From what I understand of nutrition, the natural sources deliver the same nutrients in ways that our bodies can metabolize better. I'm open to trying piracetam again, but it just doesn't seem all that significant to justify even the extra cost of buying it (and the supplements) and becoming dependent on it. If someone here actually does think it's worth it, I'd be very interested in hearing from you, provided you don't own a nootropics business.
    - gwern 17y ago
      One egg isn't going to do it. One egg gets you <200mg of choline, if I remember my research right, while you need more like >1000mg/1g to really see piracetam's effects. My DNB scores improved more with piracetam+choline than just piracetam: http://groups.google.com/group/brain-training/browse_thread/thread/4f52e50ef2c0e64/b867b21b76be7895 http://groups.google.com/group/brain-training/browse_thread/...

itistoday 17y ago

I think I read that as well, but decided against it because the literature wasn't convincing enough (i.e., hearsay on forum posts), and I wasn't thrilled with ingesting, and possibly becoming dependent on so many substances.

metamemetics 17y ago
Choline is a natural compound, you can get it by eating eggs. Most people take it as a supplement the same time with piracetam, you can buy them combined as well. It's definitely discussed in research as well as forums: http://www.ncbi.nlm.nih.gov/pubmed/7301036 http://www.ncbi.nlm.nih.gov/pubmed/7301036 "The results of these studies demonstrate that the effects of combining choline and piracetam are quite different than those obtained with either drug alone"
- itistoday 17y ago
  Thanks for the pubmed link, didn't see that. As far as choline goes, I eat an egg every day, and get my vitamins and minerals from fresh fruits, veggies and legumes. Just as you can obtain Vitamin-C or choline from a supplement, so too can you obtain them from natural sources. From what I understand of nutrition, the natural sources deliver the same nutrients in ways that our bodies can metabolize better. I'm open to trying piracetam again, but it just doesn't seem all that significant to justify even the extra cost of buying it (and the supplements) and becoming dependent on it. If someone here actually does think it's worth it, I'd be very interested in hearing from you, provided you don't own a nootropics business.
  - gwern 17y ago
    One egg isn't going to do it. One egg gets you <200mg of choline, if I remember my research right, while you need more like >1000mg/1g to really see piracetam's effects. My DNB scores improved more with piracetam+choline than just piracetam: http://groups.google.com/group/brain-training/browse_thread/thread/4f52e50ef2c0e64/b867b21b76be7895 http://groups.google.com/group/brain-training/browse_thread/...