I have used Knockout to create some pretty complex pages. Without knowing how many pages or use cases for your large app, it would be hard to say. I have mixe

I have used Knockout to create some pretty complex pages. Without knowing how many pages or use cases for your large app, it would be hard to say. I have mixed Knockout and JQuery together to handle the AJAX queries in some cases. I have also utilized the animation aspects of JQuery withing Knockout. I would tell you, a few days to a week for a pretty complex page including testing if you are fairly well versed in Knockout.