3 ms·
T cells proliferate when they see their target antigen. This technology is being used without CRISPR in a number of clinical trials. See here: http://www.cancer
by rgejman 10y ago
T cells proliferate when they see their target antigen. This technology is being used without CRISPR in a number of clinical trials. See here: http://www.cancer.gov/about-cancer/treatment/research/car-t-cells http://www.cancer.gov/about-cancer/treatment/research/car-t-...
- maga 10y agoThanks for the correction, I didn't know T cells multiply by themselves. Yet I assume they don't hang around permanently and will be sooner or later replaced by new, unmodified, cells produced by the body, hence, why I was asking about making permanent changes.
- rgejman 10y agoMaybe. We haven't been doing this long enough to know. T cells can divide into a T "memory" type, but I'm not sure if CAR-T cells do this.