4 ms·
Does anyone know why the manufacturer was pushing q12h dosing so strongly? As an opiate user, I don't want large, infrequent doses - I want small, but frequent,
by stordoff 10y ago
Does anyone know why the manufacturer was pushing q12h dosing so strongly? As an opiate user, I don't want large, infrequent doses - I want small, but frequent, doses to maintain a consistent level of pain relief without side-effects (e.g. euphoria, nausea)
Fortunately my current codeine prescription ("take 15-30mg as directed as required") gives me a fairly wide latitude - most days I don't need it at all, but on a bad day can take 15mg every three hours or so.
- xkcd-sucks 10y agoA less frequent dosing schedule is an 'improvement' over formulations which are available as generics. This justifies the patent/ increased cost of using the oxycontin or whatever's replaced it
- khuey 10y agoThe big selling point of 12 hour dosing is you don't wake up in the middle of the night in pain.
- stordoff 10y agoFair point. I use tamazepam for my sleep issues (generally they are for reasons other than pain) so hadn't really thought about that.
- jonknee 10y agoWell the big selling point for the manufacturer is that it's patented and has no generic equivalent. It's no matter if the new feature doesn't really work.
- sukilot 10y agoThe claim is that the large does are time-release. But your point re variable need is still relevant.
- ars 10y agoThe q12h dosing is patented. The regular dosing is generic. That's all. OxyContin would not exist if not for q12h dosing.