Actually I would say that you are more likely to be correct if you wait until there are multiple replicated results before you "have to accept" it as true. One

Actually I would say that you are more likely to be correct if you wait until there are multiple replicated results before you "have to accept" it as true. One study is interesting evidence, depending on the protocol, but publication bias/filedrawer effect is a real thing and studies are massively biased towards positive results.