I think most hardcore fitness people would die early. DNA telomeres can "turn over" a roughly fixed number of calories in a lifetime (2000 * 365 * 80). If you i

I think most hardcore fitness people would die early. DNA telomeres can "turn over" a roughly fixed number of calories in a lifetime (2000 * 365 * 80). If you increase your rate of caloric burn, and increase your rate of caloric consumption, you burn through your telomere's ability to use the energy. And then you experience cell death that much sooner. Getting the right amount of exercise, not too much and not too little, is the best way to increase longevity.