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First the article says: "drill holes in their molars, treat the tooth pulp that contains adult dental stem cells with low-dose laser treatments, applied tempora

First the article says: "drill holes in their molars, treat the tooth pulp that contains adult dental stem cells with low-dose laser treatments, applied temporary caps" Then it says: "Dave and his team have added an innovative, noninvasive and remarkably simple but powerful tool" Yeah, okay, if you read Wiktionary it defines "noninvasive" as "not requiring an incision". So by that strict definition it's true. Drilling holes is totally different than "an incision". Right? I realize that this has "a host of applications", some of which truly are noninvasive. It's just that this particular application was anything but noninvasive, IMO.

sah2ed 10y ago
Seems you skimmed the article. The first part you quoted was explaining the prior art done by the lead author -- giving rodents (not humans) damaged tooth. The innovative procedure on humans will use lasers to trigger restoration of the damaged teeth.
- PhantomGremlin 10y ago
  Seems you skimmed the article. I did not skim the article. Show me where it clearly says that they have an "innovative procedure" that noninvasively triggers human dentin stem cells. They alluded to other noninvasive uses, but this wasn't one of them.
habosa 10y ago
I assumed the drilling was to simulate tooth decay and to remove something to be grown back as a trial, did I read it incorrectly?
- PhantomGremlin 10y ago
  did I read it incorrectly? The way I interpreted it, they drilled into teeth from the top in order to reach the "adult dental stem cells" (see item #3 here which is dentin: https://en.wikipedia.org/wiki/Human_tooth#/media/File:Cross_sections_of_teeth_intl.svg https://en.wikipedia.org/wiki/Human_tooth#/media/File:Cross_...). The dentin stem cells are probably contained within the dentin? They wanted to stimulate the dentin stem cells with the laser light, but there is no way to reach dentin without drilling through the outer tooth enamel. They're not simulating tooth decay, they simply need to get to the dentin. Their conclusion was that this laser treatment "triggered the enhanced dentin formation".

sah2ed 10y ago

Seems you skimmed the article. The first part you quoted was explaining the prior art done by the lead author -- giving rodents (not humans) damaged tooth. The innovative procedure on humans will use lasers to trigger restoration of the damaged teeth.

PhantomGremlin 10y ago
Seems you skimmed the article. I did not skim the article. Show me where it clearly says that they have an "innovative procedure" that noninvasively triggers human dentin stem cells. They alluded to other noninvasive uses, but this wasn't one of them.

habosa 10y ago

I assumed the drilling was to simulate tooth decay and to remove something to be grown back as a trial, did I read it incorrectly?

PhantomGremlin 10y ago
did I read it incorrectly? The way I interpreted it, they drilled into teeth from the top in order to reach the "adult dental stem cells" (see item #3 here which is dentin: https://en.wikipedia.org/wiki/Human_tooth#/media/File:Cross_sections_of_teeth_intl.svg https://en.wikipedia.org/wiki/Human_tooth#/media/File:Cross_...). The dentin stem cells are probably contained within the dentin? They wanted to stimulate the dentin stem cells with the laser light, but there is no way to reach dentin without drilling through the outer tooth enamel. They're not simulating tooth decay, they simply need to get to the dentin. Their conclusion was that this laser treatment "triggered the enhanced dentin formation".