My setup would be native Linux and on top Windows/macos. Using Proxmox as your host os you get a ZFS root filesystem with ZFS compression, SSD cache, Snapshots

My setup would be native Linux and on top Windows/macos. Using Proxmox as your host os you get a ZFS root filesystem with ZFS compression, SSD cache, Snapshots. Then you install Windows and maybe try to figure out if you can run MacOS in KVM. The idea would be to leave the host system rather clean, and maybe even add a Linux guest in Proxmox. Then in the host you just install a minimal xserver (maybe with i3) and log into your virtual machines via Spice/VNC/RDP. (Maybe add Zerotier on all guest for easy networking) This way you can get all the benefits of ZFS and use the Proxmox backup functionality and do not have to reboot your system. At least this is my plan for a new workstation setup. :) Instead of Proxmox, OmniOS (Illumos) together with pkgsrc (for xserver) might be an option. (Sorry for typos. On mobile )