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A 15 year old bug in a basic package used by fMRI software was, according to the researchers, causing numerous false positives in previously published studies.
by efoto 10y ago
A 15 year old bug in a basic package used by fMRI software was, according to the researchers, causing numerous false positives in previously published studies. Which means some of the accepted fMRI based brain studies results are dubious.
- hammock 10y agoThey were dubious anyway
- hmahncke 10y agoAs I read it, the bug was a minor issue. The bigger issue is the general false positive rate, which isn't a bug exactly, but more like a statistical modeling question - with millions of vocals, what's the appropriate way to characterize an activation as spurious?
- zbjornson 10y agoNo, that was a side note about a bug that caused a ~10% increase in false positives. The real primary issue is that the clustering methods assume Gaussian autocorrelation distributions, which don't exist in reality. They estimated a 70% false-positive rate because of this http://m.pnas.org/content/early/2016/06/27/1602413113 http://m.pnas.org/content/early/2016/06/27/1602413113