Those are major advances that happen very very rarely. The bulk of science is small incremental steps in science. It is extremely frustrating not being able to

Those are major advances that happen very very rarely. The bulk of science is small incremental steps in science. It is extremely frustrating not being able to trust the results published even in high impact journals. This is a particularly glaring problem for theoreticists/modelers. Each theory/model must rely on potentially hundreds of studies, and it's really hard to assign a confidence level to each of them.