6 ms·
It's cuz p21 regulates the cell cycle (mitosis). p21 is a CDK inhibitor. CDK is necessary for the cell cycle to proceed past "checkpoints". So when you have p21
by zackattack 17y ago
It's cuz p21 regulates the cell cycle (mitosis). p21 is a CDK inhibitor. CDK is necessary for the cell cycle to proceed past "checkpoints". So when you have p21, you have CDK inhibitors, so cell division doesn't proceed. No p21 = less inhibition = more growth. (And unchecked growth is one main cause of tumors).