While the idea of pursuing a 'root cause' is attractive, in many cases, including the one you point out, there is not a clear cause to be attacked. Neurodegene

While the idea of pursuing a 'root cause' is attractive, in many cases, including the one you point out, there is not a clear cause to be attacked. Neurodegeneration is a pattern of response to multiple disease processes - we can only understand the response by studying the cases in which it arises. For the tech-minded crowd, this is like wanting to create responsive designs without actually making websites to demonstrate them.