4 ms·
Which is a good reason to back things like telomere lengthening interdiction. That would work on all cancers, and cancers can't evolve around that dramatic a hu
by reasonattlm 10y ago
Which is a good reason to back things like telomere lengthening interdiction. That would work on all cancers, and cancers can't evolve around that dramatic a hurdle, so far as we know. It is a very fundamental set of machinery, and all cancers have to lengthen telomeres in order to stay ahead of the limits to replication.
Some groups are working on blocking the action of telomerase, but to make a viable treatment ALT (alternative lengthening of telomeres) will have to be blocked too, since researchers have already seen telomerase-abusing cancers turn into ALT-abusing cancers.