While it's generally true that water-soluble vitamins are hard to overdose on, it's still true that you at the very least have an abnormally high (and possibly

While it's generally true that water-soluble vitamins are hard to overdose on, it's still true that you at the very least have an abnormally high (and possibly toxic) level of the compound in your bloodstream until your kidneys can excrete it. In the case of B6, it apparently takes years of overdose before the sensorimotor neuropathy becomes apparent: https://en.wikipedia.org/wiki/Vitamin_B6#Toxicity https://en.wikipedia.org/wiki/Vitamin_B6#Toxicity