3 ms·
Actually, the placebo controlled trials are in line with the earlier "miraculous" studies. 50% of the people in the placebo arm experienced remission [1]. Also,
by cpncrunch 10y ago
Actually, the placebo controlled trials are in line with the earlier "miraculous" studies. 50% of the people in the placebo arm experienced remission [1]. Also, studies have shown that the placebo effect in C.Dificile is up to 90% [2].
[1] http://onlinelibrary.wiley.com/doi/10.1111/pim.12175/full http://onlinelibrary.wiley.com/doi/10.1111/pim.12175/full
[2] http://jama.jamanetwork.com/article.aspx?articleid=1916296 http://jama.jamanetwork.com/article.aspx?articleid=1916296
- js2 10y agoRe [2], are we reading the same study? "Based on the available data regarding efficacy of FMT and relapse rates with standard antimicrobial therapy, we elected not to perform a placebo-controlled or active standard-treatment comparator trial." Aside: I suffered a spell of C. Diff and wouldn't wish it on my worse enemy. It is by far the worst suffering I've ever had to endure.
- cpncrunch 10y agoSorry, it looks like I pasted the wrong study. Here it is: http://www.medscape.com/viewarticle/853175 http://www.medscape.com/viewarticle/853175 (google "Mixed Results for Fecal Transplant in First Randomized Trial" to bypass the paywall).