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> With the exception of people whose brains simply do not work as they should Exactly the people these treatments target. I'm on of those people and I have nev

> With the exception of people whose brains simply do not work as they should Exactly the people these treatments target. I'm on of those people and I have never thought I could "chew on some shrooms and listen to the Grateful Dead for a couple of hours." Quite the opposite. Depression makes you think nothing will work. When I'm in a depressed state it takes a tremendous amount of will to do anything, including taking medication of any sort or even getting out of bed for that matter. Fortunately SSRIs work for me, as well as tight control of my diet and exercise. Exercise alone has never made a difference for me, though. One of the worst episodes I ever had came at a time when I was in the best shape of my life, working out everyday.

martin1975 10y ago
that mirrors my experience w/depression prior to having it diagnosed. I knew something was up, and tried to self medicate in a number of ways, among which dieting, exercising and long term fasting was present. Everything seemed to help a bit, kind of mask the turmoil of the anxiety and panic that was going on, but eventually my 'nature' took over and I'd go back to feeling like doomsday's around the corner... SSRI seems to have done the trick. Apparently we all produce "normal amounts" of serotonin, but with depressed folk like myself, the serotonin doesn't hang on the synapse long enough ...i.e. our specific biology depletes it faster. Looking at my wider family, this condition is so pervasive ... and inherited, it's not even funny in all the ways it wreaked havoc on people's lives in many ways. Glad I caught a break.
- stuxnet79 10y ago
  Based on your description it seems like we suffer (or in your case 'suffered') from the same condition. I've been suffering from panic-disorder since my mid-teens and it is only recently when I tried an MAOI that my doctor recommended that I've seen the condition lift a bit. There is some co-morbid depression but I believe that is a result of the anxiety and not the reverse. The MAOI is effective but my anxiety still flares up from time to time, and I've been thinking of other ways I can try to improve my state of mind. I'm not even sure how I would broach the subject of ECT, as I haven't experimented with enough drugs to know if they are all ineffective. However, these trials give me hope that in the future we will have better ways of dealing with anxiety / panic disorders. > Looking at my wider family, this condition is so pervasive ... and inherited, it's not even funny in all the ways it wreaked havoc on people's lives in many ways. Glad I caught a break. I agree, it is quite sad. Like right now I'm certain that my father is depressed although the reasons for this are somewhat interconnected with real life events like unemployment, loss of loved ones, etc ...

martin1975 10y ago

that mirrors my experience w/depression prior to having it diagnosed. I knew something was up, and tried to self medicate in a number of ways, among which dieting, exercising and long term fasting was present. Everything seemed to help a bit, kind of mask the turmoil of the anxiety and panic that was going on, but eventually my 'nature' took over and I'd go back to feeling like doomsday's around the corner... SSRI seems to have done the trick. Apparently we all produce "normal amounts" of serotonin, but with depressed folk like myself, the serotonin doesn't hang on the synapse long enough ...i.e. our specific biology depletes it faster. Looking at my wider family, this condition is so pervasive ... and inherited, it's not even funny in all the ways it wreaked havoc on people's lives in many ways. Glad I caught a break.

stuxnet79 10y ago
Based on your description it seems like we suffer (or in your case 'suffered') from the same condition. I've been suffering from panic-disorder since my mid-teens and it is only recently when I tried an MAOI that my doctor recommended that I've seen the condition lift a bit. There is some co-morbid depression but I believe that is a result of the anxiety and not the reverse. The MAOI is effective but my anxiety still flares up from time to time, and I've been thinking of other ways I can try to improve my state of mind. I'm not even sure how I would broach the subject of ECT, as I haven't experimented with enough drugs to know if they are all ineffective. However, these trials give me hope that in the future we will have better ways of dealing with anxiety / panic disorders. > Looking at my wider family, this condition is so pervasive ... and inherited, it's not even funny in all the ways it wreaked havoc on people's lives in many ways. Glad I caught a break. I agree, it is quite sad. Like right now I'm certain that my father is depressed although the reasons for this are somewhat interconnected with real life events like unemployment, loss of loved ones, etc ...