6 ms·
The 5% was for eligibility, because other treatment options had been exhausted for that group - but presumably it could be made available for a wider range as w
by blitzd 10y ago
The 5% was for eligibility, because other treatment options had been exhausted for that group - but presumably it could be made available for a wider range as well. Due to the intensity of the treatment the other 95% may opt for a different path.
The treatment is definitely rough on the body as they appear to wipe out the entire immune system via chemo, but the person who died did not die from the treatment itself.
The number of patients experiencing some sort of reversal was 8 out of the 24, or 33%. There were also 7 (I believe) who had the progress of the disease halted. The last 8 did not see the progress reversed or halted, but I was unclear on whether it progressed at the same rate or not. Regardless, it would seem that at least 70% of the participants saw a benefit.
They did also mention that of the 8 that did not see a regression or halt they believed that the cause may have been the timing of the treatment and the prior progress of the disease in those patients. I wonder if the treatment could be started quickly enough if it would be possible to see a regression in a higher number of cases?
Anyways, I wouldn't say it's really hype in any way. There's clear results, and they can likely be improved on to increase the efficacy and availability for those who suffer from MS.