Hmm... if it filled a niche, maybe. Like for example: websockets break on mobile devices because of carrier proxy servers and other issues, and if this figured

Hmm... if it filled a niche, maybe. Like for example: websockets break on mobile devices because of carrier proxy servers and other issues, and if this figured out how to handle that effortlessly and write everything in python, I could see it being the new hotness. I think frameworks often live or die by their use case/niche. That's why you have sinatra and flask, because every language needs a simple web framework. You get rails and django because you want common problems solved in opinionated ways to get you up and running quickly. I don't know that python to JS compilation so you can write isomorphic python code for your back end and front end is going to be a strong enough niche on it's own, unless you have awesome source maps and a browser plugin that make debugging super easy. But if you are just looking for a clever hack, adding some CLI tools and a reasonable license would be pretty cool IMHO.