Interesting parallel study I saw recently: Autoimmune disease rodent models don't translate well to the clinic, so an academic group tried to look for reasons.

Interesting parallel study I saw recently: Autoimmune disease rodent models don't translate well to the clinic, so an academic group tried to look for reasons. They found that normal, healthy humans have far more memory B cells than lab mice, which may be a major factor. So they looked at wild mice and pet store mice. Wild mice had a lot of memory B cells, but pet store mice had the most. They found you can house pet store mice with lab mice, and the lab mice will eventually increase the number of B cells, but you lose about 20% of them.