In Potato we did exactly this. The server side is written in Common Lisp and the client side is implemented in Clojurescript. While I have to say that it has w

In Potato we did exactly this. The server side is written in Common Lisp and the client side is implemented in Clojurescript. While I have to say that it has worked pretty well, Lisp and Clojurescript are different enough that it really isn't much of a benefit to use both together. Even the S-expression format of the two languages are so different that we need to use JSON when sending messages from the server to the client (and vice versa, of course). Please feel free to look at the code if you want to learn more about how it's done. I'll be happy to answer any questions: https://github.com/cicakhq/potato https://github.com/cicakhq/potato