I don't think "Minor" is accurate. A good friend just went through this to beat a strange form of metastatic blood cancer, and he was in the ICU for a week as a

I don't think "Minor" is accurate. A good friend just went through this to beat a strange form of metastatic blood cancer, and he was in the ICU for a week as a direct result. (and essentially comatose) It was worth it, since he went from, "Plan your death" to, "Full remission!". Still, he was strong going in, a lot of people would have died. Right now, there's still a lot of art to the balance between having your immune system fight hard enough to kill the cancer, without setting off a cytokine storm that kills you. There's also the issue of longer term autoimmune complications, which I suspect will turn out to be the "secondary cancers" of the immunotherapy world.