3 ms·
This isn't controversial at this point, it's becoming the consensus, and it isn't news. But it gives me a chance to say: if you have real "allergy" problems but
by Nomentatus 10y ago
This isn't controversial at this point, it's becoming the consensus, and it isn't news. But it gives me a chance to say: if you have real "allergy" problems but test negative for histamine/IgE allergies, say on a skin test; look into MCAS. Fair warning, your allergist may very well never have heard of it - doctors are rarely paid to read.
MCAS = Mast Cell Activation Syndrome
MCAD (Mast Cell Activation Disorder) = MCAS or mastocytosis
Great links here:
http://strengthflexibilityhealtheds.com/2016/02/04/diagnosing-mast-cell-activation-syndrome-mcas-update-and-diagnosis-confirmation/ http://strengthflexibilityhealtheds.com/2016/02/04/diagnosin...
http://www.mastattack.org/2014/10/mcad-general-information-public/ http://www.mastattack.org/2014/10/mcad-general-information-p...
http://evilmastcells.com/ http://evilmastcells.com/
http://www.jacionline.org/article/S0091-6749(14)02927-3/fulltext http://www.jacionline.org/article/S0091-6749(14)02927-3/full...
Dr. Anne Maitland’s presentation on Allergies & Mast Cell Activation Syndrome in EDS Patients. https://www.youtube.com/watch?v=ktFdr-9rpIM&feature=youtu.be https://www.youtube.com/watch?v=ktFdr-9rpIM&feature=youtu.be
https://mastcellblog.wordpress.com/mastcellguide/ https://mastcellblog.wordpress.com/mastcellguide/
- ejstronge 10y agoMastocytosis is exceedingly rare - an article in NEJM (one of the authoritative medical journals) estimates that 1 in 100,000 people have been diagnosed with the disease. If your primary care physician has 2,000 patients (not unreasonable), s/he could reasonably expect to never encounter the disorder outside of a textbook. Just as in programming, doctors avoid the 'premature optimization' - no need to test for a rare disorder until considerably more common ones, like allergies, are ruled out.