How large does a site need to be before render time becomes a significant issue? I can understand it being an issue for, say, Google News or some other highly d

How large does a site need to be before render time becomes a significant issue? I can understand it being an issue for, say, Google News or some other highly dynamic site where the input sources are programmatic. But for sites where there are humans providing the content, why in today's computing era would it take more than a minute to update hundreds of pages?