Yeah there is a certain dissonance in conducting research to create psychoactive drugs based on "anxiety-like symptoms", then giving that drug to humans and see

Yeah there is a certain dissonance in conducting research to create psychoactive drugs based on "anxiety-like symptoms", then giving that drug to humans and seeing that it does in fact cure anxiety, and the refuse to attribute that emotion to animals. How do they think that the research worked then, sheer coincidence ?