> Hypothyroidism Accounts for about 10 extra pounds on a normal-sized human. Didn't stop me from losing 35 pounds in four months when I was 100 pounds overwei

> Hypothyroidism Accounts for about 10 extra pounds on a normal-sized human. Didn't stop me from losing 35 pounds in four months when I was 100 pounds overweight. > PCOS Same as above, assuming PCOS is a cause and not an effect. There seems to be some debate on that in the Ob-Gyn community. > Cushing's syndrome Cushing's is fairly rare, and is usually curable. > complications of depression Yes, depression is a big psychological cause of overeating. Been there. Disentangling the depression from the food is part of the therapy, though. Particularly since it becomes a self-reinforcing cycle where depression begets comfort eating which begets more depression. > The accusation was that these cases are self-inflicted. It's WAY more complicated than that. Always self-inflicted? No. More complicated? Yes. However, except in rare circumstances every underlying condition is treatable or curable. There are synthetic hormones for hypothyroidism. There are cortisol blockers, surgeries, and other treatments for Cushing's. PCOS is incurable but treatable, ironically considering the subject by weight loss. Depression is treatable, though it can be a struggle. Obesity may not be self-inflicted in all cases, but it is almost always resolvable. I'm resolving it, despite having two of the things you listed. You can't just throw your hands up and complain about "conditions" as an excuse to not do anything about the problem. Hell, everything you listed has potentially serious problems if untreated even if it doesn't cause weight gain.