4 ms·
i'd start with the basics of cell biology, gene expression, and Cas-9 (wikipedia would work), then go right into "High throughput functional genomics using CRIS
by akarve 10y ago
i'd start with the basics of cell biology, gene expression, and Cas-9 (wikipedia would work), then go right into "High throughput functional genomics using CRISPR–Cas9" and work backwards from the paper to fill in the gaps in your knowledge. the paper is dense. nevertheless it gives you the grand big picture of CRISPR. this way you don't spend months learning genomics theory, some of which is already outdated.
http://www.nature.com/nrg/journal/v16/n5/full/nrg3899.html http://www.nature.com/nrg/journal/v16/n5/full/nrg3899.html
for a quick high-level view of Cas-9, there's doudna's talk https://www.youtube.com/watch?v=SuAxDVBt7kQ https://www.youtube.com/watch?v=SuAxDVBt7kQ