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To do some very basic research in math, the absolute minimum one should know is the basics of number theory, group theory and real analysis. By analogy, what's
by hiall 10y ago
To do some very basic research in math, the absolute minimum one should know is the basics of number theory, group theory and real analysis. By analogy, what's the absolute minimum knowledge for someone who wants to enter the field(as far as CRISPR goes) to at least be able to read papers and maybe do some labwork? Thanks.
- akarve 10y agoi'd start with the basics of cell biology, gene expression, and Cas-9 (wikipedia would work), then go right into "High throughput functional genomics using CRISPR–Cas9" and work backwards from the paper to fill in the gaps in your knowledge. the paper is dense. nevertheless it gives you the grand big picture of CRISPR. this way you don't spend months learning genomics theory, some of which is already outdated. http://www.nature.com/nrg/journal/v16/n5/full/nrg3899.html http://www.nature.com/nrg/journal/v16/n5/full/nrg3899.html for a quick high-level view of Cas-9, there's doudna's talk https://www.youtube.com/watch?v=SuAxDVBt7kQ https://www.youtube.com/watch?v=SuAxDVBt7kQ
- DanWebster13 10y agoI'd strongly recommend starting with the non-profit Addgene's guide to CRISPR (https://www.addgene.org/crispr/guide/ https://www.addgene.org/crispr/guide/). A great place to start and accompanying blog posts keep up to date. Also a great place to get the DNA building blocks, libraries, etc.
- deleted 10y ago[deleted]
- 100ideas 10y ago"Molecular Biology For Computer Scientists" is a decent place to start (pdf): http://www.cs.princeton.edu/~mona/IntroMaterials/hunter-bio-for-CS.pdf http://www.cs.princeton.edu/~mona/IntroMaterials/hunter-bio-...