Your points are good, but despite their entropic advantages they remain limited by the anthropic principle. Other forms are likely possible, just unlikely unde

Your points are good, but despite their entropic advantages they remain limited by the anthropic principle. Other forms are likely possible, just unlikely under our set of circumstances. I would still hazard a guess and say that I would expect carbon based life to be there basis of the lions share of life in the universe though. Regarding the Krebs cycle and other biological feedback cycles, I strongly disagree. It came to dominate at a point where it propagated through all the extant branches of life, but it is by no means the only way life could have decided to do the process of energy production. Once evolution evolves something, it is stuck with that system - no complex biochemical system will evolve into a Krebs replacement whilst Krebs occupies that niche, and evolution isn't going to spit it out of the way!