Original paper is here : http://www.cell.com/cell-reports/fulltext/S2211-1247%2816%2930298-4 http://www.cell.com/cell-reports/fulltext/S2211-1247%2816%29... CR

Original paper is here : http://www.cell.com/cell-reports/fulltext/S2211-1247%2816%2930298-4 http://www.cell.com/cell-reports/fulltext/S2211-1247%2816%29... CRISPR/Cas9-Derived Mutations Both Inhibit HIV-1 Replication and Accelerate Viral Escape Supplement here : http://www.cell.com/cms/attachment/2052606220/2059839343/mmc1.pdf http://www.cell.com/cms/attachment/2052606220/2059839343/mmc... Known strain to start with. They claim "Both viral targets are very conserved in HIV-1 sequences that are registered in the HIV database (Figure S1B)." See explanation of figure S1 in supplement for more info.