I found this comment to be much better, and more interesting, than the original article: >The other side of the third possibility is that LDL and HDL levels ar

I found this comment to be much better, and more interesting, than the original article: >The other side of the third possibility is that LDL and HDL levels are indicators of some underlying process, and not causative at all. So CETP inhibitors might just be changing the indicator while doing nothing to the actual cause of the heart disease, while statins are doing something to the underlying cause, which in turn changes cholesterol levels. IE the old “correlation is not causation” coming to bite us yet again.