While I happen to agree with you, I think that andrewf was pointing out that while modafinil is known not to be an acute toxin, that says little as to whether i

While I happen to agree with you, I think that andrewf was pointing out that while modafinil is known not to be an acute toxin, that says little as to whether it is a chronic toxin, since its mechanism is poorly understood and may have undesirable long-term side effects. A good example might be fructose, which you'd have to try very hard indeed to overdose on, but seems to be a long-term chronic toxin with many unpleasant effects, the high LD50 and the advisability of taking it at all being quite unrelated, indeed opposing.